Famous childhood infectious diseases - whooping cough, tetanus and diphtheria - are very common in adults. Moreover, recently many parents refuse to vaccinate children, which leads to outbreaks of epidemics of childhood infections, and in the near future may cause a pandemic of these diseases. Experts insist that all children, without exception, should be immunized, and to make the process not too protracted and to be immunized more easily, modern multi-component vaccines should be chosen that can immediately protect the body from a number of infectious diseases. These drugs include the Belgian vaccine Infanrix.
The essence of the drug Infanrix
Vaccination with the help of Infanrix helps to create in humans a specific immunity to three major childhood infections - whooping cough, diphtheria and tetanus. Sometimes this vaccine is also called acellular pertussis, to characterize its main difference from the domestic vaccine of a similar action called DTP.
The fact is that in the Belgian preparation there are no whole cells of pertussis infection. The destroyed parts of the antigens of bacteria that can form antibodies in humans have been added to the vaccine. This makes the drug safer for the body and purified. After all, it has long been known that the majority of adverse reactions caused by DTP vaccination are provoked by the component of whooping cough. Infanrix, compared with DTP, contains only 5 out of 3000 pertussis antigens, which reduces its allergenicity tenfold.
The fact that the weaker form of immunity from using Infanrix is not scientifically proven. This vaccine contains pertactin, tetanus and diphtheria toxoids, hemagglutinin and pertussis toxins. Pertactin and hemagglutinin also belong to the antigens of the pertussis pathogen, and the diphtheria and tetanus toxoids in the Infanrix are highly purified and inactivated by high temperatures.
Vaccination with Infanrix should be within the same time frame as standard DPT vaccination. The first vaccine should be given to a child aged 3 months. To complete the immunization cycle, vaccination is repeated at 4.5 and 6 months.
13 months after the last vaccination, revaccination is performed using the drug Infanrix. It is important to remember that the timing of vaccination due to temporary indications does not worsen the formation of immunity in the child, therefore it is better, if there are any diseases or temporary contraindications, to temporarily refrain from the injection and make it when the child is completely healthy.
Also, some specialists have not scientifically proved that if the child began to be vaccinated with Infanrix, then after it it is no longer possible to produce revaccination by means of DTP. In all specialized medical sources there is information that all vaccines against pertussis, tetanus, and diphtheria are completely interchangeable, and it is possible to replace single-component vaccines with multi-component vaccines and vice versa.
The drug Infanrix is required to be injected deep into the muscle. Other methods of vaccine administration do not exist. Vaccination with the use of this vaccine can be performed simultaneously with vaccination against other diseases, but the collection of different drugs in one syringe is absolutely not acceptable.
Specific immunity after vaccination with this tool begins to form a month after the third vaccination. By diphtheria and tetanus, this produces immunity in 99% of those vaccinated, and to whooping cough - in 95%. With revaccination at the age of 18 months, the secondary response of the immune system increases the result after the primary triple vaccination. In general, the Infanrix vaccine forms a strong immunity to all three diseases in 88% of children.
Contraindications, side effects and complications
The main contraindications for the use of the drug Infanrix doctors include:
- the presence of allergic reactions to vaccine type DPT;
- encephalopathy detected within a week after a previous immunization with the use of Infanrix (while vaccination against tetanus and diphtheria continue to be carried out by other means, since this reaction is usually characteristic of the pertussis component);
- fever after previous vaccination, large edema at the injection site, shock conditions, convulsions.
With all the above contraindications, doctors do not cancel revaccination at all, but try to carry it out with the help of other vaccines whenever possible.
Among the side effects when using the Infanrix vaccine, experts highlight the occurrence of local reactions at the injection sites, an increase in body temperature, the occurrence of vomiting and loose stools, loss of appetite, and allergic manifestations.
All of the above side effects may occur normally within three days after immunization. In the first half hour after the injection, you should stay in the hospital so that doctors have the opportunity to arrest the emerging angioedema or anaphylaxis in a timely manner.
Most often after the introduction of Infanrix, the child's body temperature rises to 38-39 degrees (less often to 40) and redness occurs at the site of the drug. These symptoms should completely go away on their own after 3 days of severity.
The temperature these days can be shot down with ordinary antipyretic agents. At the same time, in the room where the immunized child is located, it is often necessary to air the baby, it is necessary to water the baby himself. With sudden temperature fluctuations, the occurrence of seizures and other severe symptoms, it is necessary to urgently seek medical help and not self-medicate.
All of the above complications and side effects can be avoided if you prepare in advance for vaccination. Infanrix, due to the absence of whole-cell pertussis bacilli, in itself affects the children's body more gently than DTP. Moreover, if each subsequent vaccination is harder than the previous one, it makes sense to replace the vaccine with another one. So you can weaken the immune system response to the introduction of the drug.
Also, before vaccination is not recommended to feed the child, because in this case, the vaccine has a better effect on the body. Also, doctors advise to clean the child intestines on the eve of immunization, if this does not occur naturally, you can make microclysmicism.
After vaccination, you should also not eat much at once, it is better to follow a diet that day. New products should not be introduced into the diet of the child either before or after vaccination for at least a week. It is also undesirable to bathe the child on the day of vaccination.
Most importantly, on the eve of the vaccination, the doctor must necessarily examine the child and draw up a conclusion about his full health. With recent contact with people suffering from respiratory infections, vaccination should be slightly delayed.
A complete analogue of the vaccine Infanrix is only the domestic drug DTP. In the other vaccines, analogues, in addition to components from whooping cough, tetanus and diphtheria, there are other components.
For example, in the vaccine Tetrakok has also been added the anti-polio component, as in the vaccine Infanrix IPV. The drug Infanrix Hex contains components aimed at combating whooping cough, diphtheria, tetanus, hemophilic infection, polio and hepatitis B. All the same components, except for the antigen to hepatitis B, are in the vaccine Pentaxim. Well, the drug Bubo Coc consists of antigens similar to DTP, plus the antihepatitis component.
Thus, we can conclude that the highly effective Belgian vaccine Infanrix, which helps in the formation of human immunity against the three most common infections - whooping cough, diphtheria and tetanus - is a better and safer analogue of the domestic DPT vaccine.
The absence in the composition of the drug whole cell component of whooping cough makes vaccination easier for children to digest immunity. At Infanrix, doctors observe significantly fewer adverse reactions from vaccinated organisms. To minimize the likelihood of an increase in temperature after vaccinations, experts recommend that children be prepared in advance for them. In the event of adverse reactions of the body, it is important to promptly seek medical help.